Pebbles was born at the Bedrock Rockapedic Hospital on February 22, 10,000 B.C. weighing 6 pounds (according to the series' producers, though that particular year was never actually cited within the show itself; most versions of the show put the Flintstones' era as circa 1,000,000 B.C.).
While an infant, the Flintstones' next-door neighbors the Rubbles adopted the super-strength possessing infant Bamm-Bamm; Pebbles and Bamm-Bamm quickly became lifelong best friends.
As a pre-teen, Pebbles was an excellent baseball player, which of course led to a misadventure involving her father Fred (as seen in the primetime special The Flintstones: Little Big League).
By the time she was a teenager, Pebbles was noted for getting her cohort Bamm-Bamm and their friends, Wiggy, Moonrock, and Penny, into various misadventures, mostly due to sharing her father's penchant for schemes that would inevitably backfire (such as causing a strike by Bedrock's city employees when she was elected honorary mayor for a week). She and her friends attended Bedrock High School and she also had a catchphrase similar to Fred's: "Yabba-Dabba-Doosie!"
As an adult, Pebbles pursued a career in advertising and married Bamm-Bamm. After this, the newly-married couple moved to Hollyrock (a fictional prehistoric version of Hollywood, California). They eventually have twin infants, son Chip and daughter Roxy.