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Susan Murphy/Ginormica, a normal woman who is hit by a radioactive meteor on her wedding day, causing her to mutate and grow to a height of 49 feet 11 inches (15.21 m). Meek and unassertive, she just wants to return to her old life, but gradually warms up to her new status as a monster. In addition to her size, she is amazingly strong and has a resistance to energy attacks. She serves as the film's central character.

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